I must say that I don't have the feeling of running a conversion. Most of all because my group focuses on the roleplaying, and partly because WotBS is so awesome. 
What WotBS does right is focus on the role playing, the characters and the non-player characters. It really is a setting that takes you in and it's a lot of fun both as a DM and a player.
I think the most important part with WotBS is that it isn't a dungeon crawl.
Something I didn't see before running the module is that it's really easy to play some of the more interesting NPC's in the module. They are so believable and interesting that they in themselves lift the module above the usual cut. Focus on this and I think you can put it in nearly any setting.
Secondarily is the issue mentioned by Tricky110974 - it's a conversion and it's noticeable. At least the first module. Some of the skill challenges feel a bit clunky and so does some of the encounters. As mentioned above - it really doesn't matter. Focus on the story, the NPC's and make it believable. Fixing encounters is minor business compared to fixing inconsistencies, confusing NPC's and unbelievable plots.

What WotBS does right is focus on the role playing, the characters and the non-player characters. It really is a setting that takes you in and it's a lot of fun both as a DM and a player.
I think the most important part with WotBS is that it isn't a dungeon crawl.
Something I didn't see before running the module is that it's really easy to play some of the more interesting NPC's in the module. They are so believable and interesting that they in themselves lift the module above the usual cut. Focus on this and I think you can put it in nearly any setting.
Secondarily is the issue mentioned by Tricky110974 - it's a conversion and it's noticeable. At least the first module. Some of the skill challenges feel a bit clunky and so does some of the encounters. As mentioned above - it really doesn't matter. Focus on the story, the NPC's and make it believable. Fixing encounters is minor business compared to fixing inconsistencies, confusing NPC's and unbelievable plots.