I'd need to see a citation showing that their difference in hand shape was that extreme, but even if so, no, probably not. Or we would notice just like we notice if someone has an oddly long thumb. If they speak a language you know about, if not one you know, and walk upright, and have a human face, and wear clothes and want Starbucks, at most we are gonna wonder what happened to their hands.
Hell, people with 6 fingers exist, and most of the time we haven't assumed they were witches, much less that they werent human.