Some companies have a bad reputation for how they treat their franchise owners. Schlotzsky's (a chain of sandwich restaruants for our UK friends) would nickle and dime their franchise owners by over charging on supplies they were contractually obligated to purchase from them. This made it difficult for them to stay in business and they ended up closing a lot of stores.
In a Hell on Earth, a post apocalyptic version of Deadlands, mutants receive a penalty to their Charisma because they are disliked and mistrusted by humans. In one campaign I ran, one of the players decided to play a mutant, and just about everywhere his character went I made it clear that his was a presence unwelcome by many. This was a case where the player and the GM simply had different ideas of what it meant to be a mutant. Based on his decision to play a mutant, I just assumed this was the kind of play experience he wanted. It wasn't.