Fortunately for my group and I, 4e is simply D&D. Same as OD&D, 1e, 2e, 2.5e, 3e, and 3.5e.
We've never played D&D as a video game, and never will as long as its on paper.
Similarities? I guess, if you only stick to going from room to room killing things and having brief, pre-scripted...