First: Bestow Curse and Feeblemind: Nasty combo.
Second. Cursed items. Recently, I ran into a Periapt of Health +4 and, what, for some odd reason, I deduced before I got someone to Analyze Deowmer and nat-20 the rolls, a curse. Foul Rotting. I mean, that's just nasty.
Now. I'm in a low magic...