I do believe he's referring to n-sided 3d objects being extruded into 4d (or possibly higher).
I think some of the difficulty arises in the method of "Extrusion" used. Consider a square, and a circle. Brought from 2d to 3d, the square becomes a cube, and generally you think that the cirlce becomes a sphere. Except that if you use the same extrusion method on the circle as the square, you'll get a cylinder instead. If you use the same extrusion method on the square as you used to get a circle into a sphere, you'll... also get a cylinder. In order to produce both a cube and a sphere, you need to use different methods.
So... what method are you using the extrude your hyperpyramid? Hyperdiamond? Hyperdecahedron? Hyperduodecahedron? Etc? The method used will alter the topography drastically, as seen in my 2d->3d example above. Unless you can define the translation, you can't define the number of sides.