1) what are the key campaign points you've gotten from 1 & 2? What do the PCs think they're supposed to do?
I'm not entirely sure - they've generally been focused on the action - Tsuto and then Nualia in Burnt Offerings, with Aldern Foxglove and Xanesha in Skinsaw. They've found out some stuff on the Runelords, but have not acted too much on it yet - however, the modules don't really give them too much to act upon - it seems it's more like "for your information"
2) What is the culmination of the campaign you imagine? If you could meander any which way, but you had a last page of the book already written, how would you end it?
2.5) In fact, for this campaign, what are the peices of the puzzle you still need to give them? Like, if they had to get five parts of an amulet for the end, and already found 2, you'd need to give them the remaining 3 in order to use the dungeon beyond the door the Amulet opens.
No clue right now - the last campaign was a bit more clearly defined and it was one of those epic save the world from Armageddon campaigns. However, the last campaign was also not "revealed" until the PCs were level 5 or so, which is like level 7 in 4E.
3) What are things the party has built in terms of a home base for themselves? Sandpoint or Magnimar?
Several of the PCs are from in or around Sandpoint, including the party wizard's father owning a small shop in town and the shaman and fighter both having farms just outside of town.
4) What kinds of encounters do you want to run? Dungeon crawls? City investigations? Battlefield melees? Exploring ruins? Chases through the wilderness, or over rooftops? NPC interactions/negotiations?
5) What kinds of encounters do your players want to play? (see above)
I generally prefer to have encounters in the wilderness rather than in a dungeon, though I don't mind any of the encounter types on your list. My group is kind of built based on the last campaign where most of the encounters were in open spaces (forest, desert, plains, savannah, hillside, mountainside, etc) that gave both sides lots of room to move. However, last campaign, they did have a group diplomat and got involved in a lot of social encounters... this time out, they do not.
Based on how they "built" their characters this time, I think they prefer the more wide-open spaces types of encounters.
Thanks - a lot of good advice.