In the world I'm developing, clerics aren't a core class -- they're a prestige class that can be taken around 4th level, and their progression of abilities is greatly limited. So I have to agree with the accordance of sainthood to most clerics and knights of the churches; they're a chosen few, sponsored into the clergy from the laity, brought into the mysteries of the faith. In this world, however, not even the churches know that the gods they worship don't exist -- but they are limited to casting 4th level cleric spells.
On the flip side, druids do not meet with this restriction, hence cleric becomes a decidedly flavored class in my world; people become clerics because they wish to be show they represent a belief structure, not so they can beat people over the head with a mace in the name of a god, while raining down his 'righteous' judgement (which, IMO, is how most clerics I've seen played come off). Any shmoe can do that...
Overall -- I like the great sacrifice. I also like the possibility of recovering the Kajh of Destruction (the orbs I referred to earlier) and somehow destroying them. Also, in my realm, there is an opposing set of Kajh, and I might work something in about those.
Here's a question, though -- does passing ones' self off as a god truly make one a god, or does it make one evil? Is not the act of deception (epsecially of this magnitude) so morally base and wrong?