No, PCs are special in a couple of areas:
1) They get a favourable fixed number of hit points per level. NPCs either get the roll or the average value, depending on how much of a hurry I'm in.
2) A PC subjected to direct damage cannot be reduced from any positive hit point value to anything less than -1. A PC at 0 or fewer hit points does not have this protection, and it does not apply to NPCs, familiars, animal companions, cohorts, or anyone else, no matter how important to the plot.
3) PCs use point buy for their stats. NPCs have whatever stats I think are appropriate.
Why?
The PCs are special, by virtue of being the stars of the show.
Also, I vastly prefer letting the dice lie where they fall. To reduce unexpected deaths, and mortality in general, I've stacked the odds in favour of the PCs in advance, which gives me a bit more (perceived) freedom to run the game as I prefer.