Flame Seed only creates a zone of fire if it hits your target, so he'd still have to roll an attack against the creature in the square.Would you allow a druid to throw his acorn on the ground at the square that a foe occupies creating a zone around the foe just by hitting the ground?
Generally, no. You can attack a square (and you have to if you're fighting an invisible creature), but the rules dictate that to attack a square you make an attack roll against a creature in that square, and if there's no creature in the square, you miss.There is also a part that says that a DM may allow you to attack objects with attacks that normally target a creature.
PHB Errata:
Target [Addition]
Player’s Handbook, page 57Add the following sentences to the end of the first paragraph: “Some powers include objects as targets. At the DM’s discretion, a power that targets a creature can also target an object, whether or not the power lists an object as a potential target.”
Is the ground not considered an object?