Use Guide would be a synergy-only skill. For every 3 ranks in it that you have, choose either a Knowledge or Profession skill, a skill useful for hanging around in not-so-classy places, or a skill useful for being a general criminal. You gain a +2 bonus on checks with that skill.
seeing Don't Panic in large friendly letters would remove the effects of fear for one round. At the end of the fear-free round, repeat the initial save that caused you to become scared in the first place, with a +2 bonus. If you fail, you resume being freaked out, and will not gain any benefit from seeing the words Don't Panic for the duration of the fear effect. If you succeed, you are released from the fear effect. Also, seeing Don't Panic doubles the rate at which you regain Sanity.