(Note: this post is about the behavior of groups of NPCs. It's not about ASIs, and it's not about how individuals behave, especially PCs.)
I don't think we need to be absolutist and say that it's impossible for some species to have hard-wired behaviors, which may or may not be an evolutionary result of different physiology.
It's just that so many attempts to do this in RPGs have failed to be very creative, and instead have ended up as some variation on the way Europeans have traditionally described people they want to subjugate, and in the game this has been a shorthand for "It's ok to kill me!".
So I think by trying to avoid bioessentialism, and trying to rely on cultural explanations for group behaviors, we can avoid lazy characterizations that evoke actual evil. (That's the irony: relying on some tropes as shorthands for evil, we are actually mirroring genuine evil.)
(ninja'd by @Crimson Longinus )
As good as real-life people are at renaming/reframing things so they can still talk down about the groups they want to, and humanity's penchant to target others based on nationality, religion, or whatnot, I don't think the cultural explanations will do what people want either - and we will still get the irony you mention. It feels like even occupational related ones will need some care to avoid blue-collar vs. white-collar and urban vs. rural stereotypes.