Oh yeah I'm definitely looking to a publisher, but given the size of the book (300 pages, hard cover, black and white), and the fact that it's a campaign setting, I don't think it bodes well for the pickup. Granted, the setting already has a community of 1000+ fans, and I can get about 60 to 100 pre-orders, but I have not had much luck over the past few days getting it picked up. Couple of nibbles, but that's it so far.
Running a business doesn't scare me, given that I've got an MBA, and I already run a business that manages the Avlis servers. However, I have no expertise in the publishing field, which is why I'd rather get a publisher than go it alone.
Again, if not, I'll just keep preparing the manuscript one step at a time (i.e. art, editing, layout, etc.) and then going to print at lulu.com or something.