Demetrios1453
Hero
I can't see them doing "just" Tomb of Horrors. Not enough there, there.
I could see them doing an AP loosely based on the S-series (Tomb, White Plume, Barrier Peaks, Tsojcanth). Although they'd probably remix it (like Strahd) and maybe drop Barrier Peaks (D&D is less sci-fi genre-mixey friendly than it used to be).
The thing about dropping Barrier Peaks is that VGtM just updated two monsters that originated in that module and mentioned their alien origin in the text...