Hmm. Thramnë is a native of Mistledale, but has been away for a few years, and is only just returning. He could be returning from practically anywhere in western Faerun. It would not be unusual for lone travelers to band together for protection when traveling along the Black Road, in particular if they spurn Zhent protection along the way.
They probably start their journey at Llork, a large town on the western end of the Black Road, situated along the valley of the River Grayflow. Leaving Llork, which is overtly controlled by the Zhents, travelers ascend and pass through the Graypeak Mountains by using the Dawn Pass, heading east. Skirting the Lonely Moor, they arrive at the great wastes of Anauroch, and after long weeks, leave the deserts to cross the northern tip of the Desertsmouth Mountains. They quickly descend to the headwaters of the River Tesh, and the narrow valley that contains the only town in Daggerdale, Dagger Falls. Here they might hear of trouble in Mistledale. Thramnë would certainly have only more reason to head home, but might persuade people of proven character to accompany him to relieve the people of his home Dale.
The way to Mistledale would take them from Dagger Falls, across rugged hills of shrubs and thickets to Shadowdale. From the current home of the Sage, a lesser road of greater danger leads along the northern banks of the River Ashaba through a mighty arm of the forest of Cormanthor, ancient home of elves. The road leaves the forest and arrives from the northwest into Ashabenford, the largest settlement of Mistledale, surrounded on all but the west by ancient forests.