Right now, I'm playing a wide variety of games. My weekly 3e game just ended, and we've only played 3e twice in my other gaming club. Most of the people there don't like the new system for strange reason - probably because they don't want to buy new books or bother to do things like read all the rules.
So we play a homebrew fantasy game, some weird space game which uses elements of the home-brew space system that we used to play, SpaceMaster (chartmaster in space), and the ships - modified to fit the spacemaster propulsion stuff - from Jovian Chronicles and one DM is looking to start an Aftermath game since he ended his Shadowrun game when we were about to kill each other.
I have Alternity and now HERO, but I haven't played them often. I haven't played a game of HERO yet actually, which is good because I haven't made a character that I really like yet.