While waiting for the poll to change, shall just write my answer. I'm currently playing:
4th Edition D&D
Cthulhutech
I am hoping of starting another New World of Darkness game soon, either a Geist game (coming out soon), or get around to doing a full Hunter game. Also Eclipse Phase if it does come out soon (supposed to be coming out soon). Also a Shadowrun Anniversary Edition game when Cthulhutech is done.
We're pretty much playing 3.5E exhaustively right now. I wouldn't mind playing other stuff, but we don't really have the time or inclination to change right now.
We played some RQIII last year, and agreed to go back to D&D, so it isn't like we haven't tried something different...
I voted that I play 3E, but I also play Pathfinder in equal measure (and perhaps will play it more once the final version comes out), but I picked 3E, because it is the basis for Pathfinder anyway (and because the final version of Pathfinder is not out yet). This poll really needs to be multiple-choice.