I use SAGA to run my pulp Masked Alliance 1930s mystery men/super heroes game. I allow a few feats from Mutatns and masterminds, and allow talents to buy M&M powers if there doesn't seem to be a better way to buy them, and is working fine. I find Black Bat, Captain Lightning, Crime Hunter, the Human Rocket, Mystara and her Magical Menagerie and Yeoman have exactly the Saturday Morning Serial feel I wanted when they face down Ghengis Ceasar or the Shadow Syndicate.
I also created a "goon" thug class with no steps on the condition track and no level bonus to saving throws. It works greak for mooks.