UniversalMonster
Explorer
I would love to see a Monster/NPC Builder, but let's not get ahead of ourselves.
The monster builder is at D&D Insider
You use the same one for NPCs in 4th Edition, although lately, when I stat up non combat NPCs I do it like so:
Fizzbein (mayor): Diplomacy +9, History +7
Shalamat (sage): Arcana +12, Religion +12, History +15
..because I don't assume they'll be in any combat.