Ugh. No thanks. Adventure Paths are generally well written but they are huge pain to run out of the book. Tons of important information is buried in walls of text. I actually asked on the forums about this, and James Jacobs responded by saying that lots of people buy the APs to read them, not run them, so changing to a more playable format (bullet points and lists rather than heavy prose, for example) just was not going to happen.
I have several PF APs but haven't run any of them. IMO adventures should have a lot more flow charts and bullet lists of important information. Stuff that can easily referenced.