Hi,
I've been running Bastion of Broken Souls weekly for about four months (short sessions, mostly 2-3 hours each). The players generated PCs specifically to play the adventure -- they wanted to experience high-level play.
At the beginning, there were regular PC deaths, but with true resurrection available to the party cleric, this hasn't put them off. When I realized they weren't tough enough, we added another PC bringing the total to six plus Nurn (NPC in the adventure) and they are now getting through the adventure fairly easily although they have learned to be cautious and are resting in Mordenkainen's Magnificent Mansion after almost every single encounter. Their party tactics have also got loads better -- they were non-existent at the start.
Not sure I'd recommend it though -- there's an interesting plot and some colourful encounters, but it's getting a bit wearing.
I also ran Sunless Citadel, The Standing Stone and the much-maligned Deep Horizon. Sunless Citadel is a good 1st-level adventure, The Standing Stone makes a change from dungeon-crawling, and Deep Horizon is good if you can play up the roleplaying aspects by getting the players engaged in the plight of the desmodu.
Cheers
Richard