1) What will happen to Greyhawk? Is WOTC going to publish Greyhawk material or close down the setting again? If it does choose to publish, will the 4 Adventure Paths and various smaller Greyhawk adventures (like the Fiend's Embrace) count as "canon" or not? If it does not choose to publish, will it let Greyhawk go to a loving home, like Paizo, or will it keep it in the vault?
2) Will there be a replacement for Dungeon? A place where DM's can get cheap, high quality modules on a regular basis.
3) Does WOTC care about old school customers? Are we a drag on your image as you try to sell to WoW users, or do you actually care about pencil-and-paper gamers who are too old to have piercings?
4) Is WOTC a gaming company, or a marketing division for a consumer products firm?