I was thinking recently about this again, and low and behold the thread pops back up. Since the show seems to enjoy borrowing concepts the concept I would like to see borrowed more is from Andromeda (The show has grown on me). The thing that makes that show different from other shows is something that they have dirrectly refered to as "one man's will to reshape the universe". I can't think of another show off the top of my head that focuses on this as a possitive thing, it is always the bad guy who is normally doing this and therefore needs to be stopped.
While Enterprise should and cannot become Andromeda, I would like to see Archer pick up a little of this and start to have some concept of what he is doing out there. Even if it is not starting the Federation exactly, he should be at least dreaming that there could be something more for humans and aliens and working on toward that end. Instead he seems perfectly content bouncing from place to place with no goal and no worries (other than will I be fired) whenever he makes major diplomatic mistakes.