Well, white dragons leap immediately to mind as an arctic apex predator. I guess it depends on what sort of big beastie you're looking for. Frost Worms are CR 12 I believe, rehmorazes (I'll leave the correct spelling and plural of that to others) are about that, then there's winter wolves (who are only around a CR 4 but I think that number's soft... I've had a lot of bad luck with winter wolves). In the giant range there are Frost Giants and Ice Trolls.