DispelAkimbo
Explorer
One simple option is to take the standard setting and move the timeline on a milenia or so.
The current npcs become figures of history, with one or two (like Elminster probably
) still around.
Wars have of course occured in the mean time, nations risen, some fallen, gods changed portfolios, died and re-born, new laws and traditions arise, new races arrive, cataclysms occur, plagues etc.
Simply decide how much change you want from the custom setting and try to logically work out how long that change will have taken, then set your campaign in that year in the future.
The current npcs become figures of history, with one or two (like Elminster probably

Wars have of course occured in the mean time, nations risen, some fallen, gods changed portfolios, died and re-born, new laws and traditions arise, new races arrive, cataclysms occur, plagues etc.
Simply decide how much change you want from the custom setting and try to logically work out how long that change will have taken, then set your campaign in that year in the future.