I find these can be hard to get player buy-in, so I think some flexibility will be required to make it work.
This is where backgrounds and subclasses make a huge difference. Someone mentioned an "eco-fighters" campaign with only druids and rangers.... but what about a rogue scout? A paladin oath of the ancients? A wizard with the outlander background? So if you have that one player that won't play along, a compromise can be found...
All wake up Reborn - Mongrols stitched up from parts of defeated adventurers from some deathtrap dungeon. - That one could be a serious roleplay or very very silly. "That's my arm! Give it back!" "Kiss your ass"
Yes, it's interesting that Eddings did really well with the Belgariad with extremely varied stereotypes in the party, and the managed to do almost as well (it's a bit less "young adult", but honestly his transition to more mature subjects still feels a bit woody to me) with an almost all paladin cast.