Interesting to see, of the named choices, that Clive Owen leads the way. As for the other choices, well, I've made my points in the other thread about non-British actors playing Bond so that leaves:
Ewan McGregor: too famous... therefore would cost too much to hire. Has also said he doesn't want to commit to another series of films.
Ioan Gruffudd: good actor, but if the Fantasic Four does well, could be committed to that
Jason Isaacs: another good actor but, again, tied to a series of films at the moment (Harry Potter).
Orlando Bloom: like others have said, a little too young (at 27) however, definately one for the future.
Sean Bean: for the same reason that Connery will never play a Bond villain, Bean will never play Bond. Unfortunate as he's another good choice.
BTW, my money (IRL) is on Clive Owen
