i just started a new group. i had two players already, my wife and my best friend. i needed at least two more. one of the new players came from the gamers seeking gamers board, and he seems to be fitting in pretty well. the other new player came from work, where i approached people who i knew played crpg's, wrote fiction, or even read the same type of books i do. he's also fitting in pretty well.
i was always too scared to approach the games at my local gaming store. they were all played in the back room, from which you would occasionally hear whiny arguing. it seemed very clannish, too...
and if you work from home and don't have many friends, set up some weekly socializing or something. sign up for art classes or karate or ball room dancing or even a sci fi/fantasy reading club. you've got to get outside every now and then... once you get to know and like a few people, ask them if they're interested.