The early settlers in Arkansas were not known for their creativity. Any DM would be laughed at for:
Lake City, Lake View, Portland, Harbour, Lake Shore and Bay none of which is anywhere near a body of water. Lake Village is actually on a lake, but the lake in question was once a river. Or Lake Georgia (three states away) Pacific (half a dozen states away)
How about these original names: Black Rock on the banks of the Black River not far from the confluence with the Spring River, which eventually runs into the White river. Or Springfield, Oak Dale, Black Oak (there are three black oaks in Arkansas not counting the band of the same name), Fairview, Hot Springs, Mammoth Spring, Mineral Springs, Pump Springs, Sulfur Springs, Pine Bluff, Greenville, Daisy, Star City, Gravel Junction, Bald Knob, Riceville, Cotton Plant, Forrest City, Bare Stone, Strong (reached by the strong hwy), Rose Hill, South Bend, West Point, Newport, Red Hill, Midway, Mountain Home (no doubt settled by dwarves), the Elves are over in Mississippi at Greenwood, the halflings can be found along the banks of the Little Red River, and Four Groves where the Druids get together, or Crater of Diamonds (no doubt a dragons lair), Kilgore, Bleaker and Croak (Orc and goblin country), Lost Valley (certainly adventure to be found there) and who could forget the Capital Little Rock or as someone else mentioned the border town with Texas Texarkana and there is an Arkansas City though I don't think it is big enough to qualify as a town much less a city under the current rules.
There is abundant Plant and animal life in the region too: Buck Snort, Elk, Pike City, Bear Grease, Possum Grape, Fish Dock, Grapevine, Willow, Otter, Reedville, The Buffalo River, Swan Lake, Bull Shoals, Lake Beaver Lake and Toad Suck.
Given what most people think of Arkansans we have the aptly named Cornie and Hicksville. Its not all bad with Hope, Hopewell, New Hope, Delight, Joy, Bragg, Ball and Peace.