Ruin Explorer
Legend
I think the question to be asked here is what role vampires and werewolves fill in your setting, what do you want from them? Do you want them to be primarily scary antagonists, with PCs as less-powerful members? Do you want them to be just people dealing with difficult issues? Do you want the werewolves to shift voluntarily/at will? Do you want vampires to be hurt by the sun, or is the default that the thin-blooded PC vampires are daywalkers? Or perhaps PC vampires default to having a ring that protects them?
I think you need a pretty firm conception of what you want from them and what you're intending to do with them before you can start designing them.
Also are they ancestries? Presumably one is not born a vampire, though born a werewolf is pretty common, but again not always the case.
If I was just going with "I want them to be about the same power level as existing ancestries", I'd be looking at "dilute" versions of both - i.e. some kind of toned-down werewolf where you didn't have a Crinos-form equivalent, you were just a person who could turn into a wolf (giving you the T1 predator template from Druids maybe, it's rather wolf-esque) and healed fast, so on a short or long rest you added +2 to your rolls to heal HP. With vampires I'd probably make them thin-blooded-type neonates, and I'd consider what aspect of vampirism I wanted to emphasize - In a modern-day setting I'd probably go with blood-drinking as one of them and to avoid disturbing issues make it only possible to be used on consenting targets by the PC ancestry-type vampires (NPC vampires, all bets are off), and say they don't need to eat/drink, but they do need to drink blood at least once a week or something, and that doing so does 1 HP of damage to the consenting target but also heals 3 HP on the vampire, and they can gain this benefit 1/long rest or something. For their other ability I'd probably be looking at something combat-related - would you want to emphasize their speed, strength, toughness?
I do think generally Daggerheart would make a very strong base for an Urban Fantasy setting, and modern guns would be pretty trivial to add (just ignore the bad design on the revolver and make them work more like the magic revolver or something).
