The Dark Power of Friendship - Set in a cutesy My Little Pony or Carebears type world but the twist is that the villains are a close knit Manson Family-esque cult who have full access to the Power of Friendship, Power of Love, and the Indomitable Force of the Human Spirit. Alternately you could dial that back to just the Power of Love and have the villains be a criminal power couple like Bonnie and Clyde, or Fred and Rose West whose relationship is built around a shared interest in violent crime.
