Like many older gamers, I've played and DMd every edition from 1 to 4e. When I was younger, I could devote much more time to learning all the spells, and rules and charts etc., but now there is less time to spare. This fact alone makes 4e a better game for me and the old friends I play with. DMing 4e is 100% easier than past editions, and playing is easier, yet still enjoyable.
When my friends and I changed from hardcore teen players, who had nothing better to do than play the game, to casual, once a month or so players, it was impossible to keep in character and remember all of the spells that a wizard, cleric, or other spell caster could use. Now, we can play and then pick up the game in one, two or even 3 months and still be able to run characters effectively.
I actually remember at one point how playing higher level characters in our infrequent games gave me anxiety attacks - Try to infrequently play a Druid 12/Wizard 12 from any earlier edition and you'll panic too.
I've also found that because the powers in 4e are much easier to use/remember, the players I play with spend more time roleplaying and getting into the character rather than trying to optimize spell effects. In addition, combat tactics are also more interesting in 4e.
I guess I really like 4e. There..I said it. All the hardcore old-timers can crucify me now.
Cheers.