Wow!
Just wow.
Some of my immediate thoughts, in no particular order:
* Non-random hit-points!! If you are as terrible at rolling dice as I am, this means a lot!
* Only one defense bonus - wasn't expecting that, but it *is* consistent with 3e.
* Number of healing surges apparently depends on one's class. Didn't expect that either.
* I'm not terribly pleased with being told I *have* to take Thievery - though it will depend on just exactly what that skill does. But it's easy enough to house-rule that you just pick six off the list.
* I was expecting Bluff and Intimidate to be folded together; guess not. I'm also surprised that "Insight" (Sense Motive?) isn't part of Perception.
* Confirmation that humans still get an extra feat at 1st level, looks like. And it looks like it can be any feat - we know Toughness isn't human-exclusive. It also appears that humans are the only race to get bonus feats.
* A feat called Backstabber... since they've already got Sneak Attack, I wonder just what this does?
* 1st level characters get 2 at-wills, 1 encounter power, and 1 daily power. I wonder how that ratio holds up with more levels?
* You can use some Charisma skills in place of attacks. Interested to see how it's done these days - I love playing taunting, laughing rogues.
* Brutal Scoundrel: Huh. Don't you already get Str bonus to your Sneak Attack? Guess not. Artful Dodger looks tasty too.
* A little bit of love for daggers - and shuriken, of all things.
* Sneak Attack: Do crits let you max this out also? Brutal, if so.
* Powers: Most add Dex-mod to damage; Brutal Scoundrels can add Str on top of that for some of them. But then why does it say under "Brawny Rogue" that Str adds damage "directly"? Is there any option to do a plain-vanilla attack, as opposed to an at-will power? (I think surely there must - surely wizards don't *have* to use spells, they can swing a staff if they wish.)
* Crimson Edge is NASTY. Easy to see why it's a per-day power. Torturous Strike looks like it'll be a wasted power beyond 20th level - or perhaps not, I'm not sure how the per-encounter stuff works yet. It does look like they're working hard to make low-level powers still viable later on.
* Powers apparently don't shift categories as you go up in level. Once an encounter power, always an encounter power, or so it seems.
This has definitely whetted my appetite for more!