Hi, deletedmemory! There are a couple of us prowling the forums, but not too many.
Both Hand of Evil and myself are from the Palmetto State, and a couple of other posters who aren't nearly so regular. However, neither of us are from your neck of the woods - i'm from the Florence area, myself. Rel's a Raleigh, NC gamer, so he's even farther.
However, you're near Clemson territory, there ought to be quite a bit of gaming in the area - you may want to call local game stores for references, if the forums don't pan out, because many game stores have bulletin boards for "calling all gamers." Wish I could help more, though.
*EDIT*
Slaps forhead one other alternative - if you can't find any live gaming action, have you considered the ENWorld Play-By-Post forums? They're not face-to-face, but we've got hundreds of members who regularly game this way, either for fun or because location and circumstances force this to be their only gaming outlet.