It would be interesting if the spell ripped the weave and gave thousands (or whatever number is manageble campaign-integrity wise) of the inhabitants magic immunity (can't use and can't be affected by it). Red Wizards without any power, peasants now immune to magical control. Maybe even a Zulkir affected.
Or maybe, it threw thousands of inhabitants out of phase, so now they all are permanently blurred or displaced.
Or maybe, it threw thousands of inhabitants out of phase, so now they all are permanently blurred or displaced.