Pirates of Dark Water was a super niche cartoon that only had 2 seasons and no reboots.
The fact that it is constantly brought up in nostalgia and mentioned for reboots displays the very high appeal it had despite only being incomplete due to production and cost issues.
That's what you want as a DM. A setting that hooks into players' memories without needing a bunch of sessions to do so.
Big influence on my Islands World setting. No humans (well, as far as the PCs know), but everything else is on the table, and exists somewhere.
First session I ran for my wife and our girlfriend a few years ago, I had their “uncle” Orrobo the Grung Ranger accompanying them, they were both elf/orcs, they got hired by a Shadar-Kai, and then teamed up with a kenku and a tortle, not to mention all the gnomes, Minotaurs, Goliaths, dwarves, various cat people, Dragonborn, and others.
I still managed to have about half a dozen distinct cultures that are not primarily or entirely one race, but it brought into the spotlight something that tends to more go unnoticed when it’s all humans.
That is, not all members of a culture have the same history within that culture, and most cultures tend to have some degree of mixing of people whose ancestors were from far off, and met up in a migration period or via gradual immigration, or more unsavory things like raid prisoners, enslavement, “taking home a foreign wife” (which tends to be somewhere between the previous two), etc.
That dynamic is impossible to ignore when the Capetian apothecary is a dwarf, his best friend from back home is a frog person, and his wife is a gnome, but they’re all Capetian, all have some variety of “not-French” accent, and all have complex feelings about the Eladrin nobility of Capet, and grudges against the soldiers and nobility of Albarón, ancient rivals of Capet.
