Of the three campaigns I ran that lasted 6+ months, not one of my players took the Profession skill.
I do believe adding game mechanics to the skill, such as giving synergy bonuses to other skills that have a connection with a particular profession, is a good way to add life to this almost neglected skill.
I do believe adding game mechanics to the skill, such as giving synergy bonuses to other skills that have a connection with a particular profession, is a good way to add life to this almost neglected skill.