Destil
Explorer
3E brought us standardized conditions, but 4E simplified them.
Strength damage (3E) vs. the weakened condition (4E) is probably one of the biggest contrasts in terms of how easy it is to work out how the condition affects a character on the fly.
Every time someone asks me about why I prefer 4E I mention the 3E game I ground to a halt for half an hour with a level 1 spell.
"So, what does Ray of Enfeeblement do to the snake, then?"
"Is it's strength score odd, or even?"