I would much prefer to play a game (any game) with no house rules at all. House rules complicate the game.
But I do have a handful of house rules for my D&D3.5 campaign. I specifically did not want to rewrite the game, or throw the balance all out of whack, or drive my Players nutty trying to remember everything. I have one major house rule (concerning darkvision and lowlight vision), and five or six minor house rules.
The major house rule has effects throughout the game, but really only on a minor, almost just cosmetic, level. Its effects can be seen/felt fairly often, but it does not stagger the play. Most PCs can go through a campaign and never really be affected by this one change.
The minor house rules are really more on the level of gentleman's agreements I've put down on paper.
I have thought up many more house rules, mostly minor, but I've limited the actual rules to just those things that really stick in my craw and annoy the crap out of me on a conceptual level.
For instance, it really bothers me that the spell touch attack rule breaks all the other rules of combat -- a caster can cast a spell, move, then touch a target *in the same round*. That is a standard action, a move action, and a standard action. This break in the system annoys me deeply, even though it will rarely come up in a game. I've ruled that a caster can't put a move in between the cast and touch *in the same round*. Even though this would rarely come up in a game (has never so far in a few dozen games I've seen), I've set the rule on paper just to make me feel better. I probably could leave out this house rule, never have to deal with it, and have one less official house rule.
But not fixing a rule like this bothers me like not straigtening a crooked picture frame in the hallway. It is just sloppy.
So that is my issue with house rules.
Quasqueton