I don't see a big problem with it. A couple things I predict:
Wizards slightly more powerful. Instead of spending feats on item creation, they can spend their bonus feats on metamagic.
Bard, Paladin, and Ranger will have new powers (at high levels). You never hear about bards making items, and its even less that you hear about paladins or rangers (although it is possible, Caster level 3 (Wondrous) is only 6th level for them and they can always have someone else cast the spell for them to make the item).
Clerics, Druids, and Sorcerors will have more breathing room when it comes to an already limited feat selection.
While Jester mentioned experience and gold as limiting factors I think the biggest is time. In a harried campaign, you can take 5 item creation feats and just not have the game time to use them to much effect. Sure potions and the like only take a day, but to craft something worthwhile you generally need time, at least a week (7,000 gp item). 3.5 alleviates this somewhat as you can divide up crafting times, work on it for a couple days, adventure, then when youre back in town work on it a little more.
I also think 3e is generally too customizable. Some things should be left to chance (random treasure tables) and dm perogative, imo. This doesnt mean the character shouldnt be able to craft a few items they really want, it means they shouldn't be looking through the DMG like its an equipment guide, outfitting their characters ala The Matrix.
Technik