Herobizkit
Adventurer
Honestly, marco, I believe that your 'crazy crossovers' are what's causing the campaign to have no focus. The only central theme I can see is 'utter chaos'. This is fine... but you need a story in there somewhere to keep the players focused. I think a sandbox-style game is not well-suited for a wide-open 'anything goes' game... since anything goes, there's nothing (or very little) to tie the players together.