Midnight can be a good fit with 4e, but only if you go the Big Damn Ironborn Heroes route, not the Scavenging for Rotten Turnips route. To that end:
1. Inherent Bonuses
2. Almost no money, no economy, so no item crafting. Items are what you take from the bad guys - and most of those are Evil and unuseable anyway.
3. No Divine power source, except for the bad guys - Clerics & Paladins of Izrador are fine, obviously.
If you want to do permanent damage to PCs, use the Disease Track rules rather than messing with healing surges. You may want to make an Extended Rest a rare and precious thing, Rivendell style - a week in comfortable surrounds, perhaps, with an overnight rest giving say 1 HS back.
1. Inherent Bonuses
2. Almost no money, no economy, so no item crafting. Items are what you take from the bad guys - and most of those are Evil and unuseable anyway.
3. No Divine power source, except for the bad guys - Clerics & Paladins of Izrador are fine, obviously.
If you want to do permanent damage to PCs, use the Disease Track rules rather than messing with healing surges. You may want to make an Extended Rest a rare and precious thing, Rivendell style - a week in comfortable surrounds, perhaps, with an overnight rest giving say 1 HS back.