Post-Apoc is definitely doable. I actually own D20 Apocalypse, so that's certainly a possibility. Sounds like we have a few votes in that direction, so let's say it's a PA game.
That said, those of you interested in such a game, give me an idea of what sort of PA game you'd like to play. I've got a number of supplements, and really nothing is out of the question in terms of magic, cyberware, robots, etc. I'm not all that interested in mecha per se, but let's see what people would like to play.