I love it!
HAHAHAHA! I love this thread! I have laughed so many times just skimming it (love the references to "the Princess Bride" too

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Yes, "ATM machine", "PIN number" et al annoy the hell out of me too.
I prefer "NPCs" to "NPC's" - nice try with the leaving out of letters thing, but if you're going to be consistent, that would be "N'P'C's"
I think people may be just using "irregardless" when they really mean "irrespective" - it's like the earlier accidental use of "ubiquitous" instead of "ambiguous", a word is close to what you want but you can't quite remember it exactly, so you go with what IS in your brain.
"Rouge" I think is just people typing quickly on a keyboard and the timing just isn't quite right. I type "teh" for "the" all the time and don't always spot it in time, and I suspect we're noticing it less because Word etc automatically corrects a lot of that sort of stuff nowadays.
"I would like to thank my parents, God and Ayn Rand" just means he (or she) would like to thank all three. If they meant that God and Ayn Rand were his (or her) parents, that would be an appropriate use of the colon - "I would like to thank my parents: God and Ayn Rand."
I love ampersands, but only use them in paired words. "D&D", "Rick & Sarah" (if Rick & Sarah are a couple), "M&Ms".
I don't put a comma to separate the last two elements of a paired list, but would use it if it isn't actually a list but a pause between two joined but not necessarily related sentences. See my use of the commas before the "but"s in the sentence I just wrote!
I thought sarcasm was delivered mainly in how you said something rather than what someone literally said. Hence it is a lot harder to be sarcastic here in cyberspace than in real life.
I must say that I love spelling words with "s" rather than "z" - "conceptualisation" rather than "conceptualization". But I can live with the latter. But the US/British one I REALLY don't like is the dropping of the "u"s from words like "honour", "colour" and "flavour". "Honor", "color" and "flavor" just seem too truncated to me, visually speaking
I have friends from the country who pronounce "ask" as "arks". I don't correct them, I know what they mean, and it's a charming part of the character (note the use of the comma as a pause in that list of items that itsn't really a list of items

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I also wish people would use the apostrophe correctly, especially when it seems so simple to me - will "- is" make sense? "It is" can be shortened to "it's".
There's an enormous difference between the denotation of a word and its connotation - "orgy" may be literally a
"wanton party", but it's got a very strong sexual connotation. Interestingly, at what point does a word become so strongly identified with its connotatation that it becomes the denoted meaning and the previous denoted meaning becomes an "archaic usage"?

(Again, note - "with it is connotation" doesn't make sense in the above sentence

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Hahahahaha! I love it! have I said that already?
[Edit: I knew it was a colon and not a semi-colon - D'OH!!!

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