It really is a mixed bag.
Combat and monster design seems good. I would love it if "You get beat up a lot and there is a really big focus on risk." holds true even as you leave the lowest levels. For me fun and excitement has always in D&D been the greatest at levels low enough where you actually risk death. But in 5E this fades real quick, already by 5th level monsters start to struggle against optimized characters in a game with options turned on. If PF2's Bestiary is designed to handle that, it would be a huge bonus.
That it isn't for everybody is true though. The amount of math and things to keep in mind is to me manageable, but to people struggling with 5E it will be an insurmountable obstacle.
The game certainly comes across as having been designed in a vacuum - Paizo has not cared to learn much from the success of 5E, and I see few if any areas where the devs have been inspired by 5E, which really is boggling the mind when you think about it. (Why on Earth would Paizo think they can afford to ignore 5E? How could they not see that their game looks if not feels too much like 4E, a failed edition common sense tells you to distance yourself from? We might never know if it was hubris or ignorance...)
Some areas of rules design seems oddly restricted, like the way you don't get to influence your weapon, armor and save proficiencies - once you choose your class at level 1, these are locked in for you.
And then there's a couple of real howlers. There are feats and talents with such miniscule impact it will make you cry.
You are definitely asked as a player to make build choices that ultimately don't matter much, if at all.
Consumables like Talismans are so fiddly for so little benefit it's like the 4th edition of your nightmares.
(Luckily you can ignore Talismans entirely, at the price of half a dozen rulebook pages being a complete waste.)