Not even half the needed/wanted material is out, so I doubt we'll get a 2nd edition anytime soon. I'd feel a bit weird abut it if there is not even a complete world map out before they do, if ever.
Personally, I'd say that there doesn't need to be a 2E Pathfinder, because I like Pathfinder the way it is. Could there be changes made? Of course. Do I really want to buy another edition of rules for a rules system that I already like? No.
I would rather they publish a book full of rules variants--not new rules but optional rules like 3E's Unearthed Arcana which would replace what's in the Core Rulebook and Ultimate books. A spell point system might go in the book along with the bare minimum of changes to the rest of the game that would be needed (e.g. Wizards would have to spend all their points at the beginning of the day and have a pre-written spell list to use all day, whereas Sorcerers could spend their points as needed and not have to choose anything beforehand).
Not publish it for at least another decade?
Since we play it quite happily with no house rules, I'm very satisfied with the game as is. No improvements come to mind (though I would like epic rules).
1. Fewer skills (a la 4E).
2. 4E-style monster and NPC design guidelines.
The biggest changes I expect to see would be in the world setting for Pathfinder RPG 2E. There is a point in time where the world setting becomes so expansive that it is beyond any hope for a new player/GM to feel that they can easily understand and access all the history and precedent created by the existing setting. Golarion has grown in under five years from a blank slate to the 2nd most detailed world setting in RPG history. Only the Forgotten Realms has had more ink spilled over it in RPG land. When you surpass Greyhawk in a mere five years? That's a LOT of detail in a very short period of time.
If you are a new Pathfinder GM, there is SO MUCH material out there that it is an extremely intimidating setting to just jump into with both feet. In another five years? It will time to put it to bed.

(Dungeons & Dragons)
Rulebook featuring "high magic" options, including a host of new spells.