This would've been a blog post, but I think my chances of getting a response are still higher here in the forums for now. That or I just don't write very compelling blog posts. 
I may be overthinking things a bit, but I'm working out a rough outline for my first full 4e campaign. I'm trying to choose the right climactic encounter, that will drive many other encounters right down through the first adventure. My choices right now are Orcus and Zehir. I've got plausible stories for both.
I made a list of monsters I could use through the levels for each, and both lists are interesting. The dark, mostly unexplored, continent I'm running this campaign on borrows a lot from south america and africa and would make sense as a homeland for the many serpents of Zehir. I've certainly never run a campaign where the players have to take on a god directly (although it might be a cliche) so it would be a new concept for my group. That said the list of followers for Orcus is really compelling with all of those cool undead and demons. It just seems iconicly evil. I've got stats for Orcus (which may make him too obvious a choice), but it'll be a couple of years before I need actual stats for either.
Two great possibilities. One campaign for the next ~2.5 years. No pressure.

I may be overthinking things a bit, but I'm working out a rough outline for my first full 4e campaign. I'm trying to choose the right climactic encounter, that will drive many other encounters right down through the first adventure. My choices right now are Orcus and Zehir. I've got plausible stories for both.
I made a list of monsters I could use through the levels for each, and both lists are interesting. The dark, mostly unexplored, continent I'm running this campaign on borrows a lot from south america and africa and would make sense as a homeland for the many serpents of Zehir. I've certainly never run a campaign where the players have to take on a god directly (although it might be a cliche) so it would be a new concept for my group. That said the list of followers for Orcus is really compelling with all of those cool undead and demons. It just seems iconicly evil. I've got stats for Orcus (which may make him too obvious a choice), but it'll be a couple of years before I need actual stats for either.
Two great possibilities. One campaign for the next ~2.5 years. No pressure.