I really hope the Sense Motive (3e) / Insight (4e) skill doesn't make it into 5e. I think it clobbers the heck out of roleplaying and common sense when PCs can just ask "is he telling the truth?" and roll a d20 and find out the answer.
(Yes, even if the DM makes the roll instead of the PC, it's still a really dumb mechanic that's stupidly harmful to roleplaying and plot development.)
If you wanna think a guy is lying, then sure, think that. Come up with a reason he's lying. Prove him wrong on something, call him out. But let's drop the idea that everyone has a fair-to-good chance to measure someone's heart rate and sweaty palms and instantly tell who is deceitful.
I feel just the opposite. I think if it's done well, Insight/Sense Motive can really add to the role-playing, especially if the players are in a situation where bluffing is not expected (i.e., meeting the high priest of a local Lawful Good church or while having an audience with the kind-hearted king, etc) You can't really call out the king while he's giving you plaudits in front of 100 of his knights, and similarly, you can't immediately prove the lawful good high priest is leaving something out while he's giving a sermon. In older editions, players would make INT or WIS checks, or similar.
Also, while spells like Detect Lie can work in some cases, you can't really have the party cleric start chanting out magic words and waving his or her symbol around while being presented to the king or high priest.
Going back to 1E days, I've also never played as player or DM that the paladin's Detect Evil as some sort of invisible evil finding radar - if a paladin wants to Detect Evil, he or she must get out their holy symbol and boldly present it in the directs where they want to detect the evil, which doesn't go over well in a rough & tumble dockside tavern...
Also, if the DM is not good at lying IRL and he's running a high bluff NPC, or maybe not adept at role-playing certain types of NPCs, a roll of the dice can also help out in those cases as well.
I don't play it as an auto-win, though. So, if somebody rolls a high Sense Motive or Insight, I would say something like, "You think the king is not telling you the whole truth," or "You have a hunch the barkeep is bluffing."
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