I'm going to have to go against consensus here. While, as typical, an awful lot depends on how the final production paints turn out, there are a good number of pretty cool minis there.
There's a nice range of humanoid adventurer-types (always important for new folks looking to get minis for their party.) For example, the Dwarf Maulfighter, Human Cleric of Bahamut, Merchant Guard, Cliffwalk Archer, Elf Conjurer, Eternal Blade, Halfling Enchanter, Halfling Rogue, and Shadar-Kai Assasin all fit this role very well. Of those, the Eternal Blade and Shadar-Kai Assasin are the two whose paint jobs concern me the most, but both have reasonably interesting sculpts and the fact that both are uncommons gives me hope that the paint jobs will be acceptable enough as well.
Of the non-humanoid/monster minis, several stand out to me as pretty dang cool. The Sphinx, Thundertusk Boar, Nightmare, Sahaugin, Shadow Mastiff, Blade Spider, Demonweb Swarm, Flame Snake, Naga, Large Fire Elemental, Ravenous Goul, and Werewolf Champion would all see a place on my table any week.
With respect to the new designs, I'm partial to the new Ettercap and Ogre. I suspect that the Blackwoods Dryad either (a) represents a 4E "plant shape" Dryad ability or (b) is the offspring of a Dryad and a tree. I'm cool with either one. However, if that is indeed what the default 4E Dryad will look like, then I'm very dissapointed. As for the male Harpy, meh. While it's not the first time D&D has diverted sharply from the source mythology, and certainly won't be the last, I'm not very stoked about the concept of male Harpies.
So, of the 60 figures, I see immediate use for 21 of them at my table. Not that dissimilar from previous sets, really.