Lanefan
Victoria Rules
I'll use my PCs as examples mostly because it's easier for me to remember what's happened to them over the years....wait, so you've seen 'em all happen to the same character over some longer time-frame?
My eponymous PC has over his career lost two limbs (an arm and a leg, at different times; and he holds a dubious record as being the only PC to lose two), lost levels on various occasions, died a bunch of times, been petrified, and (I think) aged.
Another of my PCs has lost more levels than he's gained, been petrified, died numerous times, and been aged (by ghosts) at least twice. He's also been unintentionally cloned; there were two of him for a while before they were later merged.
And there's many more like these...
I can't recall ever seeing anyone's PC suffer both limb loss and feeblemind during a career, largely because each of these so rarely occur.